Basic Information
Available from natural sources? Yes
Available from synthetic sources? Yes
Prescription required? No
NATURAL SOURCES
Beet greens
Buckwheat
Cabbage
Clams
Figs
Kidney
Lettuce
Liver
Milk
Oysters
Spinach
Watercress
NOTE: Small amounts in diet satisfy requirements, except
under unusual circumstances.
REASONS TO USE
Promotes normal red-blood-cell formation. Acts as substitute for manganese in
activation of several enzymes. Replaces zinc in some enzymes.
UNPROVED SPECULATED BENEFITS
Treats anemia that does not respond to other treatment. Prevents and treats pernicious
anemia.
WHO NEEDS ADDITIONAL AMOUNTS?
Supplements are difficult to locate, so adequate food sources
become more important.
People with recent severe burns or injuries. Those with anorexia nervosa or bulimia.
Vegetarians.
DEFICIENCY SYMPTOMS
Pernicious anemia, with the following symptoms: Weakness, especially in arms and legs
Sore tongue Nausea, appetite loss, weight loss Bleeding gums Numbness and tingling in
hands and feet Difficulty maintaining balance Pale lips, pale tongue, pale gums Yellow
eyes and skin Shortness of breath Depression Confusion and dementia Headache Poor memory
UNPROVED SPECULATED SYMPTOMS
None
LAB TESTS TO DETECT DEFICIENCY
Concentration in human plasma Measured in bioassay as part of vitamin B-12
DOSAGE AND USAGE INFORMATION
Recommended Dietary Allowance (RDA):
No RDA has been established.
What this mineral does:
Acts as a catalyst in complex reactions to form vitamin B-12.
Miscellaneous information:
This is a trace element stored mainly in the liver. Deficiency is extremely rare. Cobalt
is a necessary ingredient to manufacture vitamin B-12 in the body. A deficiency of cobalt
may lead to a deficiency of vitamin B-12 and therefore to pernicious anemia.
Available as:
Capsules: Swallow whole with full glass of liquid. Don't chew or crush. Take with meals or
1 to 1-1/2 hours after meals unless otherwise directed by your doctor. A constituent of
many multivitamin/mineral preparations.
WARNINGS AND PRECAUTIONS
Don't take if you:
Are healthy and eat a nutritious balanced diet.
Consult your doctor if you:
No problems expected.
Over age 55:
Eat a balanced diet to prevent deficiency.
Pregnancy:
No problems expected, except with megadoses. Don't take megadoses.
Breast-feeding:
No problems expected, except with megadoses. Don't take megadoses.
Effect on lab tests:
None expected.
Storage:
Store in cool, dry place away from direct light, but don't freeze. Store safely out of
reach of children. Don't store in bathroom medicine cabinet. Heat and moisture may change
action of mineral.
OVERDOSE/TOXICITY
Signs and symptoms:
In megadoses, 20-30mg per day, cobalt can produce polycythemia, enlargement of thyroid
gland and enlargement of the heart leading to congestive heart failure (See Glossary). Cobalt toxicity can cause thyroid overgrowth in
infants.
What to do:
For symptoms of overdosage: Discontinue mineral, and consult doctor. Also see ADVERSE
REACTIONS OR SIDE EFFECTS section below. For accidental overdosage (such as child taking
entire bottle): Dial 911 (emergency), 0 for operator or your nearest Poison Control
Center.
ADVERSE REACTIONS OR SIDE EFFECTS
Reaction or effect |
What to do |
Polyscythemia |
Discontinue. Consult doctor immediately. |
Enlargement of thyroid gland |
Discontinue. Call doctor immediately. |
Enlargement of heart |
Discontinue. Call doctor immediately. |
INTERACTION WITH MEDICINE, VITAMINS OR MINERALS
Interacts with |
Combined effect |
Colchicine |
May cause inaccurate |
|
laboratory studies of cobalt or vitamin B-12. |
Neomycin |
May cause inaccurate laboratory studies of cobalt or vitamin B-12. |
Para-aminosalicylic acid |
May cause inaccurate laboratory studies of cobalt or vitamin B-12. |
Phenytoin |
May cause inaccurate laboratory studies of cobalt or vitamin B-12. |
INTERACTION WITH OTHER SUBSTANCES
Some beer contains cobalt as a stabilizer. People who consume
large quantities of cobalt-stabilized beer over long periods may
develop cobalt toxicity leading to cardiomyopathy and congestive
heart failure.
|