TRIMETHOPRIM |
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TRIMETHOPRIM
BRAND & GENERIC NAMES
Apo-Sulfatrim
Bactrim
Cotrim
Novotrimel
Proloprim
Protrin
Rovbac
Septra
SMZ-TMP
Syraprim
Trimpex
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? Yes
Drug class: Antimicrobial
USES
Treatment for urinary-tract infections susceptible to
trimethoprim.
Helps prevent recurrent urinary-tract infections if taken once
a day.
DOSAGE & USAGE INFORMATION
How to take:
Tablet -- Swallow with liquid or food to lessen stomach
irritation.
When to take:
Space doses evenly in 24 hours to keep constant amount in urine.
If you forget a dose:
Take as soon as possible. Wait 5 to 6 hours before next dose.
Then return to regular schedule.
What drug does:
Stops harmful bacterial germs from multiplying. Will not kill
viruses.
Time lapse before drug works:
2 to 5 days.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Nausea, vomiting, diarrhea.
WHAT TO DO:
Overdose unlikely to threaten life. If child takes much larger
amount than prescribed, call doctor, poison-control center or
hospital emergency room for instructions.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
None expected.
Common:
Rash, itchy skin. Discontinue. Seek emergency
treatment.
Infrequent:
Diarrhea, nausea, Discontinue. Call
vomiting, abdominal doctor right away.
pain.
Headache. Continue. Call doctor when
convenient.
Rare:
Blue fingernails, Discontinue. Seek
lips and skin; emergency treatment.
difficult breathing.
Sore throat, fever, Discontinue. Call
anemia, jaundice. doctor right away.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to trimethoprim or any sulfa drug.
You are anemic due to folic acid deficiency.
Before you start, consult your doctor:
If you have had liver or kidney disease.
Pregnancy:
Studies inconclusive on harm to unborn child. Animal studies
show fetal abnormalities. Decide with your doctor whether drug
benefits justify risk to unborn child.
Infants & children:
Use under medical supervision only.
Prolonged use:
Anemia.
Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or
sunlamp.
Driving or hazardous activities:
No age-related problems expected.
Discontinuing:
Don't discontinue without doctor's advice until you complete
prescribed dose, even though symptoms diminish or disappear.
Others:
No age-related problems expected.
POSSIBLE INTERACTION WITH OTHER DRUGS
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| Diuretics, thiazide |
Unusual bleeding or |
| (see Drugs Glossary) |
bruising. |
| Flecainide |
Possible decreased blood-cell |
| |
production in bone marrow. |
| Sulfamethoxazole |
Beneficial increase of |
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sulfamethoxazole effect. |
| Tocainide |
Possible decreased blood-cell |
| |
production in bone marrow. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
None expected. |
| Tobacco: |
None expected. |
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