SULFONAMIDES |
|
SULFONAMIDES
BRAND & GENERIC NAMES
Apo-Sulfamethoxazole Protrin
Apo-Sulfatrim Renoquid
Azo Gantanol Roubac
Bactrim Septra
Cetamide SK-Soxazole
Co-trimoxazole SMZ-TMP
Cotrim SULFACYTINE
Cotrim D.S. Sulfafurazole
Gantanol Sulfamethoprim
Gantrisin SULFAMETHOXAZOLE
Lipo-Gantrisin SULFAMETHOXAZOLE &
Methoxanol TRIMETHOPRIM
Novosoxazole SULFISOXAZOLE
Novotrimel Sulmeprim
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? Yes
Drug class: Sulfa (sulfonamide)
USES
Treatment for urinary tract infections responsive to this drug.
DOSAGE & USAGE INFORMATION
How to take:
Tablet--Swallow with liquid. Instructions to take on empty
stomach mean 1 hour before or 2 hours after eating.
Liquid--Shake carefully before measuring.
When to take:
At the same times each day, evenly spaced.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
Interferes with a nutrient (folic acid) necessary for growth and
reproduction of bacteria. Will not attack viruses.
Time lapse before drug works:
2 to 5 days to affect infection.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Less urine, bloody urine, coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
None expected.
Common:
Itchy skin, rash. Discontinue. Call doctor right
away.
Headache, nausea, Continue. Call doctor
vomiting, diarrhea, when convenient.
appetite loss.
Infrequent:
Red, peeling or Discontinue. Call
blistering skin; doctor right away.
sore throat; fever;
swallowing difficulty;
unusual bruising;
aching joints or
muscles; jaundice.
Dizziness. Continue. Call doctor when
convenient.
Rare:
Painful urination; Discontinue. Call
low back pain; doctor right away.
numbness, tingling,
burning feeling in feet
and hands.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to any sulfa drug.
Before you start, consult your doctor:
If you are allergic to carbonic anhydrase inhibitors, oral
antidiabetics or thiazide or loop diuretics.
If you are allergic by nature.
If you have liver or kidney disease.
If you have porphyria.
If you have developed anemia from use of any drug.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Infants & children:
Don't give to infants younger than 1 month.
Prolonged use:
May enlarge thyroid gland.
You may become more susceptible to infections caused by germs
not responsive to this drug.
Request frequent blood counts, liver-and kidney-function
studies.
Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or
sunlamp.
Driving or hazardous activities:
Avoid if you feel dizzy. Otherwise, no problems expected.
Discontinuing:
Don't discontinue without doctor's advice until you complete
prescribed dose, even though symptoms diminish or disappear.
Others:
Drink 2 quarts of liquid each day to prevent adverse reactions.
If you require surgery, tell anesthetist you take sulfa.
Pentothal anesthesia should not be used.
POSSIBLE INTERACTION WITH OTHER DRUGS
|
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| Aminobenzoate |
Possible decreased |
| potassium |
sulfa effect. |
| Anticoagulants (oral, |
Increased |
| see Drugs Glossary) |
anticoagulant effect. |
| Anticonvulsants |
Toxic effect |
| (hydantoin, |
on brain. |
| see Drugs Glossary) |
| Aspirin |
Increased sulfa effect. |
| Calcium supplements |
Decreased sulfa effect. |
| (see Drugs Glossary) |
| Isoniazid |
Possible anemia. |
| Methenamine |
Possible kidney blockage. |
| Methotrexate |
Increased methotrexate effect. |
| Oxyphenbutazone |
Increased sulfa effect. |
| Para-aminosalicylic |
Decreased |
| acid (PAS) |
sulfa effect. |
| Penicillins |
Decreased penicillin |
| (see Drugs Glossary) |
effect. |
| Phenylbutazone |
Increased sulfa effect. |
| Probenecid |
Increased sulfa effect. |
| Sulfinpyrazone |
Increased sulfa effect. |
| Sulfonureas |
May increase |
| (see Drugs Glossary) |
hypoglycemic action. |
| Trimethoprim |
Increased sulfa effect. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
None expected. |
| Tobacco: |
None expected. |
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