QUINIDINE |
|
QUINIDINE
BRAND & GENERIC NAMES
Apo-Quinidine
Biquin Durules
Cardioquin
Cin-Quin
Duraquin
Novoquinidin
Quinaglute Dura-Tabs
Quinalan
Quinate
Quinidex Extentabs
Quinobarb
Quinora
SK-Quinidine Sulfate
BASIC INFORMATION
Habit forming? No
Prescription needed?
U.S.: Yes
Canada: No
Available as generic? Yes
Drug class: Antiarrhythmic
USES
Corrects heart-rhythm disorders.
DOSAGE & USAGE INFORMATION
How to take:
Tablet or capsule--Swallow with liquid or food to lessen
stomach irritation.
Extended-release tablets--Swallow each dose whole. Don't crush
them.
When to take:
At the same times each day.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
Delays nerve impulses to the heart to regulate heartbeat.
Time lapse before drug works:
2 to 4 hours.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS: Confusion, severe blood-pressure drop, lethargy,
breathing difficulty, fainting, seizures, coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
If the child is unconscious and not breathing, give mouth-to-
mouth breathing. If there is no heartbeat, use cardiac massage
and mouth-to-mouth breathing (CPR). Don't try to make the child
vomit. If you can't get help quickly, take the child to nearest
emergency facility.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
Hives, rash, intense Seek emergency
itching, faintness treatment immediately.
soon after a dose
(anaphylaxis).
Common:
Bitter taste, diarrhea, Discontinue. Call
nausea, vomiting. doctor right away.
Infrequent:
Dizziness, Discontinue. Call
lightheadedness, doctor right away.
fainting, headache,
confusion, rash,
change in vision,
difficult breathing,
rapid heartbeat.
Ringing in ears. Continue. Call doctor when
convenient.
Rare:
Unusual bleeding Discontinue. Call
or bruising, difficulty doctor right away.
or pain on swallowing,
fever, joint pain,
jaundice, hepatitis.
Weakness. Continue. Call doctor when
convenient.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to quinidine.
You have an active infection.
Before you start, consult your doctor:
About any drug you take, including non-prescription drugs.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Infants & children:
No age-related problems expected.
Prolonged use:
No age-related problems expected.
Skin & sunlight:
No age-related problems expected.
Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if
you drink alcohol or take medicine affecting alertness and
reflexes, such as antihistamines, tranquilizers, sedatives, pain
medicine, narcotics and mind-altering drugs.
Discontinuing:
Don't discontinue without doctor's advice until you complete
prescribed dose, even though symptoms diminish or disappear.
Others:
No age-related problems expected.
POSSIBLE INTERACTION WITH OTHER DRUGS
|
|
|
| Alkaline urine |
Slows quinidine elimination, |
| |
increases effect and toxicity. |
| Antiarrhythmics |
May increase or |
| (see Drugs Glossary) |
decrease effect or toxicity of |
| |
quinidine. |
| Anticholinergics |
Increased |
| (see Drugs Glossary) |
anticholinergic effect. |
| Anticoagulants (oral, |
Possible increased |
| see Drugs Glossary) |
anticoagulant effect. |
| Antihypertensives |
Increased antihypertensive |
| (see Drugs Glossary) |
effect. |
| Beta-adrenergic |
May slow heartbeat |
| blockers (see |
excessively. |
| Drugs Glossary) |
| Cholinergics |
Decreased cholinergic |
| (see Drugs Glossary) |
effect. |
| Cimetidine |
Increased quinidine effect. |
| Digitalis |
May slow heartbeat |
| preparations |
excessively. Dose adjustments |
| (see Drugs Glossary) |
may be needed. |
| Encainide |
Increased effect of toxicity on |
| |
heart muscle. |
| Flecainide |
Possible irregular heartbeat. |
| Guanfacine |
Increased effect of both medicines. |
| Nifedipine |
Possible decreased quinidine |
| |
effect. |
| Phenobarbital |
Decreased quinidine effect. |
| Phenothiazines |
Possible increased |
| (see Drugs Glossary) |
quinidine effect. |
| Phenytoin |
Decreased quinidine effect. |
| Rauwolfia alkaloids |
Possibly disturbs |
| (see Drugs Glossary) |
heart rhythms. |
| Tocainide |
Increased possibility of adverse |
| |
reactions from either drug. |
| Rifampin |
Decreased quinidine effect. |
| Verapamil |
Hypotension. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
Can cause fainting. |
| Tobacco: |
Irregular heartbeat. |
| Avoid. |
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