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PROGESTINS

PROGESTINS

BRAND & GENERIC NAMES

Aygestin Norlutate
Lo-Ovral Norlutate Acetate
Micronor Norlutin
Modicon 21 Ortho-Novum 1/35
Nor-O.D. Ovcon
Nor-Q.D. Ovral
Norinyl 1+35 21-Day Tablets Ovrette
Norlestrin Tri-Norinyl

BASIC INFORMATION

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? No
  • Drug class: Female sex hormone (progestin)

    USES

  • Treatment for menstrual or uterine disorders caused by progestin imbalance.
  • Contraceptive.

    DOSAGE & USAGE INFORMATION

    How to take:
    Tablet -- Swallow with liquid or food to lessen stomach
    irritation. You may crumble tablet or open capsule.
    When to take:
    At the same time each day.
    If you forget a dose:

  • Menstrual disorders--Take up to 2 hours late. If more than 2 hours, wait for next dose (don't double this dose).
  • Contraceptive--Consult your doctor. You may need to use another birth-control method until next period. What drug does:
  • Creates a uterine lining similar to pregnancy that prevents bleeding.
  • Suppresses a pituitary gland hormone responsible for ovulation.
  • Stimulates cervical mucus, which stops sperm penetration and prevents pregnancy.

    Time lapse before drug works:

  • Menstrual disorders--24 to 48 hours.
  • Contraception--3 weeks. Don't take with: Any other medicines, even over-the-counter drugs such as cough and cold medicines, nose drops, diet pills, laxatives or caffeine, without consulting your doctor. OVERDOSE SYMPTOMS: Nausea, vomiting, fluid retention, breast discomfort or enlargement, vaginal bleeding. WHAT TO DO: Overdose unlikely to threaten life. If child takes much larger amount than prescribed, call doctor, poison-control center or hospital emergency room for instructions.

    POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

    SYMPTOMS WHAT TO DO

    Life-threatening:
    Blood clot in leg, Seek emergency
    brain or lung; treatment immediately.
    hives, rash, intense
    itching, faintness
    soon after a dose
    (anaphylaxis).
    Common:
    Appetite or weight Continue. Tell doctor
    changes, swollen at next visit.
    ankles or feet,
    unusual tiredness
    or weakness.
    Infrequent:

  • Prolonged vaginal Discontinue. Call bleeding. doctor right away.
  • Depression. Continue. Call doctor when convenient.
  • Acne, increased Continue. Tell doctor facial or body hair, at next visit. nausea, breast tenderness. Rare:
  • Rash, stomach or Discontinue. Call side pain, jaundice, doctor right away. fever.
  • Insomnia, hair loss, Continue. Call doctor amenorrhea. when convenient.

    WARNINGS & PRECAUTIONS

    Don't take if:

  • You are allergic to any progestin hormone.
  • You may be pregnant.
  • You have liver or gallbladder disease.
  • You have had thrombophlebitis, embolism or stroke.
  • You have unexplained vaginal bleeding.
  • You have had breast or uterine cancer.

    Before you start, consult your doctor:

  • If you have heart or kidney disease.
  • If you have diabetes.
  • If you have a seizure disorder.
  • If you suffer migraines.
  • If you are easily depressed. Pregnancy: May harm child. Discontinue at first sign of pregnancy. Infants & children: Use only for female children under medical supervision. Prolonged use: No age-related problems expected. Skin & sunlight: No age-related problems expected.

    Driving or hazardous activities:
    No age-related problems expected.
    Discontinuing:
    Consult doctor. This medicine stays in the body and causes
    fetal abnormalities. Wait at least 3 months before becoming
    pregnant.
    Others:

  • Children with diabetes must be monitored closely.
  • Symptoms of blood clot in leg, brain or lung are: chest, groin, leg pain; sudden, severe headache; loss of coordination; vision change; shortness of breath; slurred speech.

    POSSIBLE INTERACTION WITH OTHER DRUGS

    Hypoglycemics (oral, Decreased effect of
    see Drugs Glossary) oral hypoglycemics.
    Insulin Decreased effect of insulin.
    Oxyphenbutazone Decreased progestin effect.
    Phenobarbital Decreased progestin effect.
    Phenothiazines Increased
    (see Drugs Glossary) phenothiazine effect.
    Phenylbutazone Decreased progestin effect.

    POSSIBLE INTERACTION WITH OTHER SUBSTANCES

    Tobacco: Possible blood clots in lung,
    brain, legs. Avoid.

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