NITROFURANTOIN |
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NITROFURANTOIN
BRAND & GENERIC NAMES
Apo-Nitrofurantoin
Cyantin
Furadantin
Furalan
Furaloid
Furantoin
Furatine
Macrodantin
Nephronex
Nifuran
Nitrex
Nitrodan
Novofuran
Sarodant
Trantoin
Urotoin
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? Yes
Drug class: Antimicrobial (see Drugs
Glossary)
USES
Treatment for urinary-tract infections.
DOSAGE & USAGE INFORMATION
How to take:
Tablet or capsule--Swallow with food or milk to lessen stomach
irritation. If you can't swallow whole, crumble tablet or open
capsule and take with liquid or food.
Liquid--Shake well and take with food. Use a measuring spoon to
ensure accuracy.
When to take:
At the same times each day.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
Prevents susceptible bacteria in the urinary tract from growing
and multiplying.
Time lapse before drug works:
1 to 2 weeks.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Nausea, vomiting, abdominal pain, diarrhea.
WHAT TO DO:
Overdose unlikely to threaten life. If child takes much larger
amount than prescribed, call doctor, poison-control center or
hospital emergency room for instructions.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
Hives, rash, intense Seek emergency
itching, faintness treatment immediately.
soon after a dose
(anaphylaxis).
Common:
Diarrhea, appetite Discontinue. Call
loss, nausea, doctor right away.
vomiting, chest pain,
cough, difficult
breathing, chills or
unexplained fever.
Rusty colored or No action necessary.
brown urine.
Infrequent:
Rash, itchy skin, Discontinue. Call
numbness, tingling doctor right away.
or burning of face or
mouth, fatigue, weakness.
Dizziness, headache, Continue. Call doctor
drowsiness, paleness when convenient.
(in children),
discolored teeth (from
liquid form).
Rare:
Jaundice. Discontinue. Call doctor right
away.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to nitrofurantoin.
You have impaired kidney function.
You drink alcohol.
Before you start, consult your doctor:
If you are prone to allergic reactions.
If you are pregnant and within 2 weeks of delivery.
If you have had kidney disease, lung disease, anemia, nerve
damage, or G6PD deficiency (a metabolic deficiency).
If you have diabetes. Drug may affect urine sugar tests.
Pregnancy:
Risk to unborn child outweighs drug benefits, especially in
last month of pregnancy. Don't use.
Infants & children:
Don't give to infants younger than 1 month. Use only under
medical supervision for older children.
Prolonged use:
Chest pain, cough, shortness of breath.
Skin & sunlight:
No age-related problems expected.
Driving or hazardous activities:
Avoid if you feel dizzy or drowsy. Otherwise, no problems
expected.
Discontinuing:
Don't discontinue without consulting doctor. Dose may require
gradual reduction if you have taken drug for a long time. Doses
of other drugs may also require adjustment.
Others:
Periodic blood counts, liver-function tests, and chest X-rays
recommended.
POSSIBLE INTERACTION WITH OTHER DRUGS
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| Nalidixic acid |
Decreased nitrofurantoin effect. |
| Phenobarbital |
Decreased nitrofurantoin effect. |
| Probenecid |
Increased nitrofurantoin effect. |
| Sulfinpyrazone |
Possible nitrofurantoin toxicity. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
| Marijuana: |
None expected. |
| Tobacco: |
None expected. |
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