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CLONIDINE

CLONIDINE

BRAND & GENERIC NAMES

Catapres
Catapres-TTS
Combipres
Dixarit

BASIC INFORMATION

  • Habit forming? No
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Antihypertensive

    USES

  • Treatment of high blood pressure.
  • Prevention of vascular headaches.
  • Treatment of dysmenorrhea and menopausal "hot flashes."
  • Treatment of narcotic withdrawal syndrome.
  • Treatment of congestive heart failure.

    DOSAGE & USAGE INFORMATION

    How to take:

  • Tablet--Swallow with liquid.
  • Patches that attach to skin--Apply to clean, dry, hairless skin on arm or trunk. When to take: Daily dose at bedtime. If you forget a dose: Bedtime dose -- If you forget your once-a-day dose, take it as
    soon as you remember. Don't double dose.
    What drug does:
    Relaxes and allows expansion of blood vessel walls.

    Time lapse before drug works:
    1 to 3 hours.
    Don't take with:
    Any other medicines, even over-the-counter drugs such as cough
    and cold medicines, nose drops, diet pills, laxatives or
    caffeine, without consulting your doctor.
    OVERDOSE
    SYMPTOMS:
    Vomiting, fainting, slow heartbeat, coma, diminished reflexes.
    WHAT TO DO:

  • Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.
  • If the child is unconscious and not breathing, give mouth-to- mouth breathing. If there is no heartbeat, use cardiac massage and mouth-to-mouth breathing (CPR). Don't try to make the child vomit. If you can't get help quickly, take the child to nearest emergency facility.
  • See EMERGENCY INFORMATION.

    POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

    SYMPTOMS WHAT TO DO

    Life-threatening:
    None expected.
    Common:

  • Dizziness, Continue. Call doctor drowsiness, weight when convenient. gain, lightheadedness upon rising from sitting or lying, swollen breasts.
  • Dry mouth. Continue. Tell doctor at next visit. Infrequent:
  • Abnormal heart Discontinue. Call rhythm. doctor right away.
  • Headache; painful Continue. Call doctor glands in neck; when convenient. nightmares; nausea; vomiting; cold fingers and toes; dry, burning eyes.
  • Insomnia, Continue. Tell doctor constipation, at next visit. appetite loss, diminished sex drive. Rare:
  • Rash, itch. Discontinue. Call doctor right away.
  • Depression. Continue. Call doctor when convenient.

    WARNINGS & PRECAUTIONS

    Don't take if:

  • You are allergic to any alpha-adrenergic blocker.
  • You are under age 12.

    Before you start, consult your doctor:

  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.
  • If you have heart disease or chronic kidney disease.
  • If you have a peripheral circulation disorder (intermittent claudication, Buerger's disease).
  • If you have history of depression. Pregnancy: Studies inconclusive on harm to unborn child. Animal studies show fetal abnormalities. Decide with your doctor whether drug benefits justify risk to unborn child. Infants & children: Use only under careful medical supervision after age 12. Avoid before age 12. Prolonged use:
  • Don't discontinue without consulting doctor. Dose may require gradual reduction if you have taken drug for a long time. Doses of other drugs may also require adjustment.
  • Continued use may cause fluid retention, requiring addition of diuretic to treatment program.
  • Request yearly eye examinations. Skin & sunlight: No age-related problems expected.

    Driving or hazardous activities:
    Don't drive or pilot aircraft until you learn how medicine
    affects you. Don't work around dangerous machinery. Don't climb
    ladders or work in high places. Danger increases if you drink
    alcohol or take medicine affecting alertness and reflexes.
    Discontinuing:
    Don't discontinue abruptly. May cause rebound high blood
    pressure, anxiety, chest pain, insomnia, headache, nausea,
    irregular heartbeat, flushed face, sweating.
    Others:
    No age-related problems expected.

    POSSIBLE INTERACTION WITH OTHER DRUGS

    ACE inhibitors: Possible excessive
    captopril, enalapril, potassium in blood.
    lisinopril (see Drugs
    Glossary)
    Antidepressants, Decreased clonidine
    tricyclic (TCA, effect.
    Drugs See Glossary)
    Antihypertensives Excessive blood-
    (other, see Drugs pressure drop.
    Glossary)
    Appetite Decreased clonidine
    suppressants effect.
    (see Drugs Glossary)
    Beta-adrenergic Possible precipitous
    blockers (see change in blood
    Drugs Glossary) pressure.
    Diuretics Excessive blood-
    (see Drugs Glossary) pressure drop.
    Ethinamate Dangerous increased effects of
    ethinamate. Avoid combining.
    Fenfluramine Possible increased clonidine
    effect.
    Fluoxetine Increased depressant effects of
    both drugs.
    Guanfacine Blood-pressure control impaired.
    Leucovorin High alcohol content of leucovorin
    may cause adverse effects.
    Methyprylon Increased sedative effect, perhaps
    to dangerous level. Avoid.
    Nitrates Possible excessive blood-pressure
    drop.

    POSSIBLE INTERACTION WITH OTHER SUBSTANCES

    Marijuana: Weakness on standing.
    Tobacco: None expected.

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