CHLORZOXAZONE

USES

Adjunctive treatment to rest, analgesics and physical therapy
for muscle spasm.

DOSAGE & USAGE INFORMATION

How to take:
Tablet -- Swallow with liquid.
When to take:
As needed, no more often than every 4 hours.
If you forget a dose:
Take as soon as you remember. Wait 4 hours for next dose.
What drug does:
Blocks body's pain messages to brain. Also causes sedation.

Time lapse before drug works:
60 minutes.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Nausea, vomiting, diarrhea, headache, severe weakness, breathing
difficulty, sensation of paralysis.
WHAT TO DO:
Overdose unlikely to threaten life. Depending on severity of
symptoms and amount taken, call doctor, poison-control center or
hospital emergency room for instructions.

POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

SYMPTOMS WHAT TO DO

Life-threatening:
Hives, rash, intense Seek emergency
itching, faintness treatment immediately.
soon after a dose
(anaphylaxis); extreme
weakness, transient
paralysis, temporary
loss of vision.
Common:

WARNINGS & PRECAUTIONS

Don't take if:
You are allergic to any skeletal-muscle relaxant.

Before you start, consult your doctor:

Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if you
drink alcohol or take medicine affecting alertness and reflexes,
such as antihistamines, tranquilizers, sedatives, pain medicine,
narcotics and mind-altering drugs.
Discontinuing:
Don't discontinue without doctor's advice until you complete
prescribed dose, even though symptoms diminish or disappear.
Others:
Periodic liver-function tests recommended if you use this drug
for a long time.

POSSIBLE INTERACTION WITH OTHER DRUGS

Antidepressants	Increased sedation.
(see Drugs Glossary)
Antihistamines	Increased sedation.
(see Drugs Glossary)
Dronabinol	Increased effect of dronabinol on
	central nervous system. Avoid
	combination.
Ethinamate	Dangerous increased effects of
	ethinamate. Avoid combining.
Fluoxetine	Increased depressant effects of
	both drugs.
Guanfacine	May increase depressant effects of
	either drug.
Leucovorin	High alcohol content of leucovorin
	may cause adverse effects.
MAO inhibitors	Increased effect of
(see Drugs Glossary)	both drugs.
Methyprylon	Increased sedative effect, perhaps
	to dangerous level. Avoid.
Mind-altering drugs	Increased sedation.
Muscle relaxants	Increased sedation.
(others, see Drugs
Glossary)
Narcotics	Increased sedation.
(see Drugs Glossary)
Sedatives	Increased sedation.
(see Drugs Glossary)
Sleep inducers	Increased sedation
(see Drugs Glossary)
Tranquilizers	Increased sedation.
(see Drugs Glossary)

POSSIBLE INTERACTION WITH OTHER SUBSTANCES

Tobacco:	None expected
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