BUTALBITAL & ASPIRIN (Also contains caffeine) |
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BUTALBITAL & ASPIRIN (Also contains caffeine)
BRAND & GENERIC NAMES
Axotal
B-A-C
Buff-A-Comp
Butalbital A-C
BUTALBITAL, ASPIRIN & CAFFEINE
Butal Compound
Fiorgen PF
Fiorinal
Isollyl (Improved)
Lanorinal
Marnal
Protension
Tenstan
BASIC INFORMATION
Habit forming? Yes
Prescription needed? Yes
Available as generic? Yes
Drug class: Analgesic, anti-inflammatory, sedative
USES
Reduces anxiety or nervous tension (low dose).
Reduces pain, fever, inflammation.
DOSAGE & USAGE INFORMATION
How to take:
Tablet or capsule--Swallow with liquid or food to lessen
stomach irritation. If you can't swallow whole, crumble tablet
or open capsule and take with liquid or food.
Suppositories--Remove wrapper and moisten suppository with
water. Gently insert into rectum, large end first.
When to take:
At the same times each day. No more often than every 4 hours.
If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2
hours, wait for next scheduled dose (don't double this dose).
What drug does:
May partially block nerve impulses at nerve-cell connections.
Affects hypothalamus, the part of the brain which regulates
temperature by dilating small blood vessels in skin.
Prevents clumping of platelets (small blood cells) so blood
vessels remain open.
Decreases prostaglandin effect.
Suppresses body's pain messages.
Time lapse before drug works:
30 minutes.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Deep sleep, weak pulse, ringing in ears, nausea, vomiting,
dizziness, fever, deep and rapid breathing, hallucinations,
convulsions, coma.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
Hives, rash, intense Seek emergency
itching, faintness treatment immediately.
soon after a dose
(anaphylaxis);
wheezing; tightness
in chest; black or
bloody vomit; black
stools; shortness of
breath.
Common:
Dizziness, drowsiness, Continue. Call doctor
heartburn. when convenient.
Infrequent:
Jaundice; vomiting Discontinue. Call
blood; easy bruising; doctor right away.
skin rash, hives;
confusion; depression;
sore throat, fever,
mouth sores; hearing
loss; slurred speech;
decreased vision.
Rare:
Diminished vision, Discontinue. Call
blood in urine, doctor right away.
unexplained fever.
Insomnia, nightmares, Continue. Call doctor
constipation, headache, when convenient.
jaundice, nervousness.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to any barbiturate or aspirin.
You have a peptic ulcer of stomach or duodenum, bleeding
disorder, porphyria.
Before you start, consult your doctor:
If you have had stomach or duodenal ulcers.
If you have asthma, nasal polyps, epilepsy,
kidney or liver damage, anemia, chronic pain.
If you will have surgery within 2 months, including dental
surgery, requiring general or spinal anesthesia.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Infants & children:
Overdose frequent and severe. Keep bottles out of children's
reach.
Use only under doctor's supervision.
Prolonged use:
Kidney damage. Periodic kidney-function test recommended.
May cause addiction, anemia, chronic intoxication.
May lower body temperature, making exposure to cold
temperatures hazardous.
Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or
sunlamp.
Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if you
drink alcohol or take medicine affecting alertness and reflexes,
such as antihistamines, tranquilizers, sedatives, pain medicine,
narcotics and mind-altering drugs.
Discontinuing:
May be unnecessary to finish medicine. Follow doctor's
instructions. If you develop withdrawal symptoms of
hallucinations, agitation or sleeplessness after discontinuing,
call doctor right away.
Others:
Aspirin can complicate surgery, pregnancy, labor and delivery,
and illness.
For arthritis--Don't change dose without consulting doctor.
Urine tests for blood sugar may be inaccurate.
Great potential for abuse.
POSSIBLE INTERACTION WITH OTHER DRUGS
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| Allopurinol |
Decreased allopurinol effect. |
| Antacids (see |
Decreased aspirin |
| Drugs Glossary) |
effect. |
| Anticoagulants (oral, |
Increased anticoagulant |
| see Drugs Glossary) |
effect. Abnormal bleeding. |
| Anticonvulsants |
Changed seizure |
| (see Drugs Glossary) |
patterns. |
| Antidepressants |
Decreased |
| (see Drugs Glossary) |
antidepressant effect. Possible |
| |
dangerous oversedation. |
| Antidiabetics (oral, |
Increased |
| see Drugs Glossary) |
butalbital effect. Low blood sugar. |
| Antihistamines |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Aspirin (other) |
Likely aspirin toxicity. |
| Beta-adrenergic |
Decreased effect of |
| blockers (see |
beta-adrenergic blocker. |
| Drugs Glossary) |
| Contraceptives |
Decreased |
| (oral, see Drugs |
contraceptive effect. |
| Glossary) |
| Cortisone drugs |
Increased cortisone |
| (see Drugs Glossary) |
effect. Risk of ulcer and stomach |
| |
bleeding. |
| Digitoxin |
Decreased digitoxin effect. |
| Doxycycline |
Decreased doxycycline effect. |
| Dronabinol |
Increased effect of both drugs. |
| Furosemide |
Possible aspirin toxicity. |
| Gold compounds |
Increased likelihood |
| (see Drugs Glossary) |
of kidney damage. |
| Griseofulvin |
Decreased griseofulvin effect. |
| Indapamide |
Increased indapamide effect. |
| Indomethacin |
Risk of stomach bleeding and |
| |
ulcers. |
| MAO inhibitors |
Increased butalbital |
| (see Drugs Glossary) |
effect. |
| Methotrexate |
Increased |
| |
methotrexate effect. |
| Mind-altering drugs |
Dangerous sedation. |
| (see Drugs Glossary) |
Avoid. |
| Minoxidil |
Decreased minoxidil effect. |
| Narcotics (see |
Dangerous |
| Drugs Glossary) |
sedation. Avoid. |
| Non-steroidal |
Risk of stomach |
| anti-inflammatory |
bleeding and ulcers. |
| drugs (NSAIDs, |
| see Drugs Glossary) |
| Pain relievers |
Dangerous |
| (see Drugs Glossary) |
sedation. Avoid. |
| Rifampin |
May decrease butalbital effect. |
| Salicylates (others) |
Likely aspirin |
| (see Drugs Glossary) |
toxicity. |
| Sedatives |
Dangerous |
| (see Drugs Glossary) |
sedation. Avoid. |
| Sleep inducers |
Dangerous |
| (see Drugs Glossary) |
sedation. Avoid. |
| Spironolactone |
Decreased spironolactone effect. |
| Sulfinpyrazone |
Decreased sulfinpyrazone effect. |
| Terfenadine |
May conceal symptoms of aspirin |
| |
overdose, such as ringing in ears. |
| Tranquilizers |
Dangerous |
| (see Drugs Glossary) |
sedation. Avoid. |
| Valproic acid |
Increased butalbital effect. |
| Vitamin C |
Possible aspirin |
| (large doses) |
toxicity. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
|
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| Tobacco: |
None expected. |
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