BETA-ADRENERGIC BLOCKING AGENTS |
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BETA-ADRENERGIC BLOCKING AGENTS
BRAND & GENERIC NAMES
ACEBUTOLOL NADOLOL Apo-Metoprolol Normodyne
Apo-Propranolol Novometoprol
ATENOLOL Novopranol
Betaloc OXPRENOLOL
Betaloc Durules Panolol
Blocadren PINDOLOL
Corgard pms-Propranolol
Detensol PROPRANOLOL
ESMOLOL Sectral
Inderal Slow-Trasicor
Inderal LA Sotacor
Inderide SOTALOL
LABETALOL Tenormin
Lopresor TIMOLOL
Lopresor SR Trandate
Lopressor Trasicor
METOPROLOL Visken
Monitan
BASIC INFORMATION
Habit forming? No
Prescription needed? Yes
Available as generic? Yes
Drug class: Beta-adrenergic blocker
USES
Reduces angina attacks.
Stabilizes irregular heartbeat.
Lowers blood pressure.
Reduces frequency of migraine headaches. (Does not relieve
headache pain.)
Other uses prescribed by your doctor.
DOSAGE & USAGE INFORMATION
How to take:
Tablet, liquid or extended-release capsule -- Swallow with liquid.
If you can't swallow whole, crumble tablet or open capsule and
take with liquid or food. Don't crush capsule.
When to take:
With meals or immediately after.
If you forget a dose:
Take as soon as you remember. Return to regular schedule, but
allow 3 hours between doses.
What drug does:
Blocks certain actions of sympathetic nervous system.
Lowers heart's oxygen requirements.
Slows nerve impulses through heart.
Reduces blood vessel contraction in heart, scalp and other body
parts.
Time lapse before drug works:
1 to 4 hours.
Don't take with:
Any other medicines, even over-the-counter drugs such as cough
and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.
OVERDOSE
SYMPTOMS:
Weakness, slow or weak pulse, blood-pressure drop, fainting,
difficulty breathing, convulsions, cold and sweaty skin.
WHAT TO DO:
Dial 0 (operator) or 911 (emergency) for an ambulance or
medical help. Then give first aid immediately.
See EMERGENCY INFORMATION.
POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS
SYMPTOMS WHAT TO DO
Life-threatening:
Congestive heart Discontinue. Seek
failure. emergency treatment.
Common:
Pulse slower than Discontinue. Call
50 beats per minute. doctor right away.
Drowsiness, fatigue, Continue. Call doctor
numbness or tingling when convenient.
of fingers or toes,
dizziness, diarrhea,
nausea, weakness.
Cold hands or feet; Continue. Tell doctor
dry mouth, eyes and at next visit.
skin.
Infrequent:
Hallucinations, Discontinue. Call
nightmares, insomnia, doctor right away.
headache, difficult
breathing, joint pain,
anxiety.
Confusion, reduced Continue. Call doctor
alertness, depression, when convenient.
impotence.
Constipation. Continue. Tell doctor at next
visit.
Rare:
Rash, sore throat, Discontinue. Call
fever. doctor right away.
Unusual bleeding and Continue. Call doctor
bruising; dry, burning when convenient.
eyes; impotence.
WARNINGS & PRECAUTIONS
Don't take if:
You are allergic to any beta-adrenergic blocker.
You have asthma.
You have hay fever symptoms.
You have taken MAO inhibitors in past 2 weeks.
Before you start, consult your doctor:
If you have heart disease or poor circulation to the
extremities.
If you have hay fever, asthma, chronic bronchitis, emphysema.
If you have overactive thyroid function.
If you have impaired liver or kidney function.
If you will have surgery within 2 months, including dental
surgery, requiring general or spinal anesthesia.
If you have diabetes or hypoglycemia.
Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.
Infants & children:
Don't give to infants or young children unless prescribed and
monitored by your physician.
Prolonged use:
Weakens heart muscle contractions.
Skin & sunlight:
No age-related problems expected.
Driving or hazardous activities:
Don't drive or pilot aircraft until you learn how medicine
affects you. Don't work around dangerous machinery. Don't climb
ladders or work in high places. Danger increases if you drink
alcohol or take medicine affecting alertness and reflexes.
Discontinuing:
Don't discontinue without consulting doctor. Dose may require
gradual reduction if you have taken drug for a long time. Doses
of other drugs may also require adjustment.
Others:
May mask hypoglycemia.
POSSIBLE INTERACTION WITH OTHER DRUGS
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| ACE inhibitors: |
Increased antihypertensive |
| captopril, enalapril, |
effects of both |
| lisinopril (see |
drugs. Dosages may |
| Drugs Glossary) |
require adjustment. |
| Antidiabetics |
Increased antidiabetic |
| (see Drugs Glossary) |
effect. |
| Antihistamines |
Decreased |
| (see Drugs Glossary) |
antihistamine effect. |
| Antihypertensives |
Increased antihypertensive |
| (see Drugs Glossary) |
effect. |
| Barbiturates |
Increased barbiturate |
| (see Drugs Glossary) |
effect. Dangerous sedation. |
| Beta-agonists |
Decreased beta-agonist |
| (see Drugs Glossary) |
effect. |
| Betaxolol eyedrops |
Possible increased beta-adrenergic |
| |
blocker effect. |
| Digitalis |
Can either |
| preparations |
increase or decrease |
| (see Drugs Glossary) |
heart rate. Improves irregular |
| |
heartbeat. |
| Encainide |
Increased effect of toxicity on |
| |
heart muscle. |
| Indomethacin |
Decreased effect of beta-adrenergic |
| |
blockers. |
| Insulin |
Hypoglycemic effects may be |
| |
prolonged. |
| Levobunolol |
Possible increased |
| eyedrops |
beta-adrenergic blocker effect. |
| Molindone |
Increased tranquilizer effect. |
| Narcotics |
Increased narcotic |
| (see Drugs Glossary) |
effect. Dangerous sedation. |
| Nitrates |
Possible excessive |
| (see Drugs Glossary) |
blood-pressure drop. |
| Non-steroidal |
Decreased antihypertensive |
| anti-inflammatory |
effect of |
| drugs (NSAIDs, |
beta-adrenergic blockers. |
| see Drugs Glossary) |
| Phenytoin |
Decreased beta-adrenergic blocker |
| |
effect. |
| Quinidine |
Slows heart excessively. |
| Reserpine |
Increased reserpine effect. |
| |
Excessive sedation and depression. |
| Rifampin |
Decreased beta-adrenergic blocker |
| |
effect. |
| Timolol eyedrops |
Possible increased beta-adrenergic |
| |
blocker effect. |
| Tocainide |
May worsen congestive heart |
| |
failure. |
| Verapamil |
Increased effects of both drugs. |
POSSIBLE INTERACTION WITH OTHER SUBSTANCES
|
|
|
| Tobacco: |
Possible irregular heartbeat. |
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