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AMPHETAMINE

AMPHETAMINE

BRAND AND GENERIC NAMES

Amphaplex 10 & 20
Benzedrine
Bexedrine
Biphetamine
Declobese
Obetrol 10 & 20

BASIC INFORMATION

  • Habit forming? Yes
  • Prescription needed? Yes
  • Available as generic? Yes
  • Drug class: Central nervous system stimulant (amphetamine)

    USES

  • Prevents narcolepsy (attacks of uncontrollable sleepiness).
  • Controls hyperactivity in children.

    DOSAGE & USAGE INFORMATION

    How to take:
    Tablet -- Swallow with liquid.
    When to take:

  • At the same times each day.
  • Short-acting form--Don't take later than 6 hours before bedtime.
  • Long-acting form--Take on awakening. If you forget a dose:
  • Short-acting form--Take up to 2 hours late. If more than 2 hours, wait for next dose (don't double this dose).
  • Long-acting form--Take as soon as you remember. Wait 20 hours for next dose. What drug does:
  • Narcolepsy--Apparently affects brain centers to decrease fatigue or sleepiness and increase alertness and motor activity.
  • Hyperactive children--Calms children, opposite to effect on narcoleptic adults.

    Time lapse before drug works:
    15 to 30 minutes.
    Don't take with:
    Any other medicines, even over-the-counter drugs such as cough
    and cold medicines, nose drops, diet pills, laxatives or
    caffeine, without consulting your doctor.
    OVERDOSE
    SYMPTOMS:
    Rapid heartbeat, hyperactivity, high fever, hallucinations,
    suicidal or homicidal feelings, convulsions, coma.
    WHAT TO DO:

  • Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.
  • See EMERGENCY INFORMATION.

    POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

    SYMPTOMS WHAT TO DO

    Life-threatening:
    None expected.
    Common:

  • Irritability, Continue. Call doctor nervousness, when convenient. insomnia.
  • Dry mouth. Continue. Tell doctor at next visit. Infrequent:
  • Dizziness; reduced Discontinue. Call alertness; blurred doctor right away. vision; fast, pounding heartbeat; unusual sweating.
  • Headache. Continue. Call doctor when convenient.
  • Diarrhea or Continue. Tell doctor constipation, at next visit. appetite loss, stomach pain, nausea, vomiting, weight loss, diminished sex drive, impotence. Rare:
  • Rash, hives; Discontinue. Call chest pain or doctor right away. irregular heartbeat; uncontrollable movements of head, neck, arms, legs.
  • Mood changes, Continue. Call doctor swollen breasts. when convenient.

    WARNINGS & PRECAUTIONS

    Don't take if:

  • You are allergic to any amphetamine.
  • You will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

    Before you start, consult your doctor:

  • If you plan to become pregnant within medication period.
  • If you have glaucoma.
  • If you have heart or blood-vessel disease, or high blood pressure.
  • If you have overactive thyroid, anxiety or tension.
  • If you have a severe mental illness (especially children). Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Infants & children: Not recommended for children under 12. Prolonged use: Habit forming. Skin & sunlight: No age-related problems expected.

    Driving or hazardous activities:
    Don't drive or pilot aircraft until you learn how medicine
    affects you. Don't work around dangerous machinery. Don't climb
    ladders or work in high places. Danger increases if you drink
    alcohol or take medicine affecting alertness and reflexes.
    Discontinuing:
    May be unnecessary to finish medicine. Follow doctor's
    instructions.
    Others:

  • This is a dangerous drug and must be closely supervised. Don't use for appetite control or depression. Potential for damage and abuse.
  • During withdrawal phase, may cause prolonged sleep of several days.

    POSSIBLE INTERACTION WITH OTHER DRUGS

    Acetazolamide Increased amphetamine effect.
    Anesthesias (general, Irregular heartbeat.
    see Drugs Glossary)
    Antidepressants, Decreased
    tricyclic (TCA, amphetamine effect.
    see Drugs Glossary)
    Antihypertensives Decreased antihypertensive
    (see Drugs Glossary) effect.
    Carbonic anhydrase Increased
    inhibitors (see amphetamine effect.
    Drugs Glossary)
    Guanethidine Decreased guanethidine effect.
    Haloperidol Decreased amphetamine effect.
    MAO inhibitors May severely increase
    (see Drugs Glossary) blood pressure.
    Phenothiazines Decreased
    (see Drugs Glossary) amphetamine effect.
    Sodium Increased
    bicarbonate amphetamine effect.

    POSSIBLE INTERACTION WITH OTHER SUBSTANCES

    Tobacco: None expected.

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