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ANEMIA, FOLIC-ACID DEFICIENCY(Megaloblastic Anemia)

ANEMIA, FOLIC-ACID DEFICIENCY
(Megaloblastic Anemia)

DESCRIPTION

Folic-acid anemia is a deficiency in the oxygen carrying capacity of the blood. It affects the blood cells, which transport oxygen to all body parts. Folic-acid anemia affects both sexes, especially infants and adolescents.
Appropriate health care includes:
  • Self-care after diagnosis.
  • Physician's monitoring of general condition and medications.

    SIGNS & SYMPTOMS

  • Fatigue and weakness.
  • Red, sore tongue.
  • Paleness.
  • Shortness of breath.
  • Nausea, vomiting, and diarrhea.

    CAUSES

  • Complication of pregnancy, when the body needs 8 times more folic acid than usual.
  • Inadequate intake or absorption of foods with a high folic acid content, such as meat, poultry, fish, cheese, milk, eggs, green vegetables, yeast, and mushrooms.
  • Alcoholism.
  • Overcooking foods, which destroys folic acid.
  • Deficiency of vitamin B-12 or vitamin C.

    RISK FACTORS

  • Pregnancy.
  • Illness, such as tropical sprue, psoriasis, acne rosacea, eczema or dermatitis herpetiformis.
  • Fad diets or general poor nutrition, especially vitamin C deficiency.
  • Surgical removal of the stomach.
  • Smoking, which decreases vitamin C absorption. Vitamin C is necessary for folic-acid absorption.
  • Use of certain drugs, such as oral contraceptives, anti-convulsants, methotrexate, or triamterene.

    PREVENTING COMPLICATIONS OR RECURRENCE

    Advice for your child or adolescent:
  • Don't drink alcohol.
  • Eat well. Include fresh vegetables, meat, and other animal proteins. Avoid fad diets. Don't overcook food.
  • Don't smoke. Smoking increases vitamin requirements.
  • Have regular medical checkups during pregnancy. Take prenatal vitamin supplements, if they are prescribed.

    BASIC INFORMATION

    MEDICAL TESTS

  • Your own observation of symptoms.
  • Medical history and physical exam by a doctor.
  • Laboratory blood studies.

    POSSIBLE COMPLICATIONS

  • Increased susceptibility to infection.
  • Congestive heart failure.

    PROBABLE OUTCOME
    Usually curable in 3 weeks with an adequate folic-acid intake.

    TREATMENT

    HOME CARE

  • If your adolescent smokes, it is important to stop.
  • If your daughter takes oral contraceptives, she should consider using another form of contraception.
  • Your child's mouth should be kept scrupulously clean by using mild or diluted mouthwash and a soft toothbrush.

    MEDICATION
    Your doctor may prescribe:

  • Folic-acid supplements. Have the child continue taking them after symptoms improve.
  • Iron supplements to take orally.
  • See Medications section for information regarding medicines your doctor may prescribe.

    ACTIVITY
    No restrictions.

    DIET & FLUIDS
    No special diet. The child should eat foods daily that are high in folic acid. The liver can store folic acid for a limited time only.

    OK TO GO TO SCHOOL?

    When appetite has returned and alertness, strength, and feeling of well-being will allow.

    CALL YOUR DOCTOR IF

  • Your child has symptoms of anemia.
  • Symptoms don't improve in 2 weeks despite treatment.
  • Symptoms of infection (fever, chills, and muscle aches) occur during treatment. ‡
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