MOLINDONE

Brand & Generic Names

Moban
Moban Concentrate

Basic Information

• Habit forming? No
• Prescription needed? Yes
• Available as generic? No
• Drug class: Antipsychotic

Uses

Treats severe emotional, mental or nervous problems.

Dosage & Usage Information

How to take:
Tablet or solution--Swallow with liquid or food to lessen stomach irritation. If you can't swallow tablet whole, crumble and take with food or liquid.

When to take:
Follow instructions on prescription label or side of package. Doses should be evenly spaced. For example, 4 times a day means every 6 hours.

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Corrects an imbalance in nerve impulses from the brain.

Time lapse before drug works:
Nausea and vomiting--1 hour or less.
Nervous and mental disorders--4 to 6 weeks.

Don't take with:
Antacid or medicine for diarrhea.
Non-prescription drugs for cough, cold or allergy.
See Interaction Section and consult doctor.

Overdose

SYMPTOMS:
Stupor, convulsions, coma.

WHAT TO DO:

• Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
• See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

Uncontrolled muscle Discontinue. Seek movements of tongue, emergency treatment. face and other muscles (neuroleptic malignant syndrome, rare); unsteady gait; difficult breathing; fever; muscle stiffness.

Common:

• Muscle spasms of face and neck, unsteady gait.
• Restlessness, tremor, drowsiness, swallowing difficulty.
• Decreased sweating, dry mouth, runny nose, constipation, headache.

Infrequent:

• Fainting.
• Rash.
• Frequent urination, diminished sex drive, swollen breasts, menstrual irregularities, depression.

Rare:

Change in vision, sore throat, fever, jaundice, abdominal pain, confusion.

Warnings & Precautions

Don't take if:

• You are allergic to any phenothiazine.
• You have a blood or bone-marrow disease.

Before you start, consult your doctor:

• If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.
• If you have asthma, emphysema or other lung disorder, glaucoma, prostate trouble.
• If you take non-prescription ulcer medicine, asthma medicine or amphetamines.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons. More likely to develop involuntary movement of jaws, lips, tongue, chewing. Report this to your doctor immediately. Early treatment can help.

Pregnancy:
Risk to unborn child outweighs drug benefits. Don't use.

Breast-feeding:
Safety not established. Consult doctor.

Infants & children:
Don't give to children younger than 2.

Prolonged use:

• May lead to tardive dyskinesia (involuntary movement of jaws, lips, tongue, chewing).
• Talk to your doctor about the need for follow-up medical examinations or laboratory studies to check kidney function, eyes.

Skin & sunlight:
May cause rash or intensify sunburn in areas exposed to sun or sunlamp. Skin may remain sensitive for 3 months after discontinuing.

Driving, piloting or hazardous work:
Don't drive or pilot aircraft until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.

Discontinuing:

• Nervous and mental disorders--Don't discontinue without doctor's advice until you complete prescribed dose, even though symptoms diminish or disappear.
• Notify your doctor if any of the following occurs: uncontrollable movements of tongue, arms and legs; lip smacking.

Others:
No problems expected.

Possible Interaction with Other Drugs

GENERIC NAME	COMBINED EFFECT
------------------------	-----------------------
Anticholinergics*	Increased anticholinergic effect.
Antidepressants,	Increased molindone
tricyclic (TCA)*	effect.
Antihistamines*	Increased antihistamine effect.
Appetite	Decreased suppressant
suppressants*	effect.
Bupropion	Increased risk of major seizures.
Carteolol	Increased tranquilizer effect.
Clozapine	Toxic effect on the central nervous
	system.
Dronabinol	Increased effects of both drugs.
	Avoid.
Ethinamate	Dangerous increased effects of
	ethinamate. Avoid combining.
Extrapyramidal reaction-	Increased frequency and severity
causing medications*	of extrapyramidal effects.
Fluoxetine	Increased depressant effects of
	both drugs.
Guanethidine	Decreased guanethidine effect.
Guanfacine	May increase depressant effects of
	either drug.
Leucovorin	High alcohol content of leucovorin
	may cause adverse effects.
Levodopa	Decreased levodopa effect.
Loxapine	May increase toxic effects of both
	drugs.
Methyprylon	Increased sedative effect, perhaps
	to dangerous level. Avoid.
Mind-altering	Increased effect of
drugs*	mind-altering drugs.
Nabilone	Greater depression of central
	nervous system.
Narcotics*	Increased narcotic effect.
Pergolide	Decreased pergolide effect.
Phenytoin	Increased phenytoin effect.
Procarbazine	Increased sedation.
Quinidine	Impaired heart function. Dangerous
	mixture.
Sedatives*	Increased sedative effect.
Sertraline	Increased depressive effects
	of both drugs.
Sotalol	Increased tranquilizer effect.
Tetracyclines*	May decrease absorption of both
	drugs.
Tranquilizers,	Increased tranquilizer
other*	effect.

Possible Interaction with Other Substances

INTERACTS WITH	COMBINED EFFECT
---------------	---------------
Alcohol:	Dangerous oversedation.
Beverages:	None expected.
Cocaine:	Decreased molindone effect. Avoid.
Foods:	None expected.
Marijuana:	Drowsiness. May increase antinausea
	effect.
Tobacco:	None expected.