FLAVOXATE

Brand & Generic Names

Urispas

Basic Information

• Habit forming? No
• Prescription needed? Yes
• Available as generic? No
• Drug class: Antispasmodic (urinary tract)

Uses

Relieves urinary pain, urgency, nighttime urination, unusual frequency of urination associated with urinary system disorders.

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid or food to lessen stomach irritation.

When to take:
30 minutes before meals (unless directed otherwise by doctor).

If you forget a dose:
Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don't double this dose).

What drug does:
Blocks nerve impulses at smooth muscle nerve endings, preventing muscle contractions and gland secretions of organs involved.

Time lapse before drug works:
15 to 30 minutes.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.

Overdose

SYMPTOMS:
Dilated pupils, rapid pulse and breathing, dizziness, fever, hallucinations, confusion, slurred speech, agitation, flushed face, convulsions, coma.

WHAT TO DO:

• Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
• See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

In case of overdose, see Overdose section.

Common:

• Confusion, delirium, rapid heartbeat.
• Nausea, vomiting, less perspiration, drowsiness.
• Constipation.
• Dry ears, nose, throat.

Infrequent:

• Unusual excitement, irritability, restlessness, clumsiness, hallucinations.
• Headache, increased sensitivity to light, painful or difficult urination.

Rare:

• Shortness of breath.
• Rash or hives; eye pain; blurred vision; sore throat, fever, mouth sores; abdominal pain.
• Dizziness.

Warnings & Precautions

Don't take if:

• You are allergic to any anticholinergic.
• You have trouble with stomach bloating.
• You have difficulty emptying your bladder completely.
• You have narrow-angle glaucoma.
• You have severe ulcerative colitis.

Before you start, consult your doctor:

• If you have open-angle glaucoma.
• If you have angina.
• If you have chronic bronchitis or asthma.
• If you have liver disease.
• If you have hiatal hernia.
• If you have enlarged prostate.
• If you have myasthenia gravis.
• If you have peptic ulcer.
• If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

Over age 60:
Adverse reactions and side effects, particularly mental confusion, may be more frequent and severe than in younger persons.

Pregnancy:
Studies inconclusive on harm to unborn child. Animal studies show fetal abnormalities. Decide with your doctor whether drug benefits justify risk to unborn child.

Breast-feeding:
Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
Use only under medical supervision.

Prolonged use:
Chronic constipation, possible fecal impaction. Consult doctor immediately.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Use disqualifies you for piloting aircraft. Otherwise, no problems expected.

Discontinuing:
May be unnecessary to finish medicine. Follow doctor's instructions.

Others:
No problems expected.

Possible Interaction with Other Drugs

GENERIC NAME	COMBINED EFFECT
------------------------	-----------------------
Antimuscarinics*	Increased effect of flavoxate.
Central nervous	Increased effect of
system (CNS)	both drugs.
Clozapine	Toxic effect on the central nervous
	system.
Ethinamate	Dangerous increased effects of
	ethinamate. Avoid combining.
Fluoxetine	Increased depressant effects of
	both drugs.
Guanfacine	May increase depressant effects of
	either drug.
Leucovorin	High alcohol content of leucovorin
	may cause adverse effects.
Methyprylon	Increased sedative effect, perhaps
	to dangerous level. Avoid.
Nabilone	Greater depression of central
	nervous system.
Nizatidine	Increased nizatidine effect.
Sertraline	Increased depressive effects
	of both drugs.

Possible Interaction with Other Substances

INTERACTS WITH	COMBINED EFFECT
---------------	---------------
Alcohol:	None expected.
Beverages:	None expected.
Cocaine:	Excessively rapid heartbeat. Avoid.
Foods:	None expected.
Marijuana:	Drowsiness, dry mouth.
Tobacco:	None expected.