DIPHENIDOL

Brand & Generic Names

Vontrol

Basic Information

• Habit forming? No
• Prescription needed? Yes
• Available as generic? No
• Drug class: Antiemetic, antivertigo

Uses

• Prevents motion sickness.
• Controls nausea and vomiting (do not use during pregnancy).

Dosage & Usage Information

How to take:
Tablet--Swallow with liquid or food to lessen stomach irritation. If you can't swallow whole, crumble tablet and chew or take with liquid or food.

When to take:
30 to 60 minutes before traveling.

If you forget a dose:
Take as soon as you remember. Wait 4 hours for next dose.

What drug does:
Reduces sensitivity of nerve endings in inner ear, blocking messages to brain's vomiting center.

Time lapse before drug works:
30 to 60 minutes.

Don't take with:
Any other medicine without consulting your doctor or pharmacist.

Overdose

SYMPTOMS:
Drowsiness, confusion, incoordination, weak pulse, shallow breathing, stupor, coma.

WHAT TO DO:

• Dial 911 (emergency) or O (operator) for an ambulance or medical help. Then give first aid immediately.
• See EMERGENCY Information.

Possible Adverse Reactions or Side Effects

Life-threatening:

In case of overdose, see Overdose section.

Common:

Drowsiness.

Infrequent:

• Headache, diarrhea or constipation, heartburn.
• Dry mouth, nose or throat; dizziness.

Rare:

• Hallucinations, confusion.
• Rash or hives, depression, jaundice.
• Restlessness; excitement; insomnia; blurred vision; urgent, painful or difficult urination.
• Appetite loss, nausea, weakness.

Warnings & Precautions

Don't take if:

• You have severe kidney disease.
• You are allergic to diphenidol or meclizine.

Before you start, consult your doctor:

• If you have prostate enlargement.
• If you have glaucoma.
• If you have heart disease.
• If you have intestinal obstruction or ulcers in the gastrointestinal tract.
• If you have kidney disease.
• If you have low blood pressure.
• If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia.

Over age 60:
Adverse reactions and side effects may be more frequent and severe than in younger persons.

Pregnancy:
Animal studies show fetal abnormalities. Decide with your doctor whether drug benefits justify risk to unborn child.

Breast-feeding:
Drug passes into milk. Avoid drug or discontinue nursing until you finish medicine. Consult doctor for advice on maintaining milk supply.

Infants & children:
No problems expected.

Prolonged use:
No problems expected.

Skin & sunlight:
No problems expected.

Driving, piloting or hazardous work:
Don't fly aircraft. Don't drive until you learn how medicine affects you. Don't work around dangerous machinery. Don't climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes, such as antihistamines, tranquilizers, sedatives, pain medicine, narcotics and mind-altering drugs.

Discontinuing:
No problems expected.

Others:
No problems expected.

Possible Interaction with Other Drugs

GENERIC NAME	COMBINED EFFECT
------------------------	-----------------------
Anticonvulsants*	Increased effect of both drugs.
Antidepressants,	Increased sedative
tricyclic (TCA)*	effect of both drugs.
Antihistamines*	Increased sedative effect of both
	drugs.
Atropine	Increased chance of toxic effect of
	atropine and atropine-like
	medicines.
Narcotics*	Increased sedative effect of both
	drugs.
Sedatives*	Increased sedative effect of both
	drugs.
Tranquilizers*	Increased sedative effect of both
	drugs.

Possible Interaction with Other Substances

INTERACTS WITH	COMBINED EFFECT
---------------	---------------
Alcohol:	Increased sedation. Avoid.
Caffeine.	May decrease drowsiness.
Cocaine:	Increased chance of toxic effects
	of cocaine. Avoid.
Foods:	None expected.
Marijuana:	Increased drowsiness, dry mouth.
Tobacco:	None expected.