General Information
DEFINITION--A rare, inflammatory condition involving the central nervous system
that causes rapid weakness and loss of sensation.
BODY PARTS INVOLVED--Central nervous system.
SEX OR AGE MOST AFFECTED--All ages, but most common between 30 and 50.
SIGNS & SYMPTOMS
Early stages:
- Muscle weakness in hands and feet, arms and legs, abdomen and chest. The weakness
spreads within 72 hours; it may create life-threatening breathing difficulty.
- Shock (weakness; faintness; cold hands and feet; rapid heartbeat; sweating).
Later stages:
- Complete paralysis (sometimes) for weeks or months.
CAUSES--Unknown, but may be an autoimmune disorder. It sometimes follows an
immunization or minor surgery.
RISK INCREASES WITH
- Recent surgery.
- Recent immunization.
- Recent illness, such as a minor respiratory infection, gastroenteritis, Hodgkin's
disease or lupus erythematosus.
HOW TO PREVENT--Cannot be prevented at present.
What To Expect
DIAGNOSTIC MEASURES--
- Your own observation of symptoms.
- Medical history and physical exam by a doctor.
- Spinal fluid analysis and electromyography (See Glossary).
APPROPRIATE HEALTH CARE
- Doctor's treatment.
- Hospitalization in an intensive care unit so condition can be closely monitored.
- A respirator may be necessary if muscles of respiration become greatly weakened.
- Plasmapheresis in severe cases (blood plasma is withdrawn from the patient, treated to
remove antibodies and replaced).
POSSIBLE COMPLICATIONS
- Paralysis of eyelid muscles, resulting in eye damage.
- Thrombophlebitis.
- Pneumonia.
- Respiratory failure.
- Pressure sores, if the person is immobilized.
- Constipation or fecal impaction.
- Chronic nerve difficulty.
PROBABLE OUTCOME--Complete recovery without residual effects in most cases. Some
persons recover in 15 to 20 days, others require a year or more. Many mechanical devices
can aid mobility until the person recovers. Adults recover better than children.
How To Treat
GENERAL MEASURES--
- The family should maintain an optimistic outlook, stay in close contact with the
patient's doctor and help by making their visits with the patient brief and as supportive
as possible.
- Additional information available from the Guillain-Barre Foundation at (215)667-0131.
MEDICATION--Your doctor may prescribe:
- Laxatives to prevent constipation.
- Cortisone drugs, although they are not always effective.
ACTIVITY--
- Remain as active as muscle strength permits. Have a family member or physical therapist
passively move and stretch muscles.
- Ongoing physical therapy as your recovery progresses.
DIET--No special diet. Drink at least 8 glasses of fluid a day to prevent
constipation.
Call Your Doctor If
- You have symptoms of Guillain-Barre syndrome.
- The following occurs during treatment: Fever. Breathing difficulty. Sores on the skin.
Vision changes. Swollen or tender calves. Constipation.
- New, unexplained symptoms develop. Drugs used in treatment may produce side effects.
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