GILBERT'S SYNDROME

General Information

DEFINITION--Increased blood levels of bilirubin (a yellow chemical byproduct of red-blood-cell breakdown). This is not a disease; rather it is a normal variant and is usually an incidental finding of routine testing.

BODY PARTS INVOLVED--Blood.

SEX OR AGE MOST AFFECTED--Both sexes and all ages, but most common in men between ages 20 and 45.

SIGNS & SYMPTOMS

• Usually there are no symptoms.
• Rarely, a slight jaundice (yellow skin and eyes), tiredness, appetite loss or upper abdominal pain may occur.

CAUSES--The liver is inefficient in changing bilirubin to bile, leaving above-normal levels of bilirubin in the blood. If blood levels are high enough, jaundice may appear. Any liver abnormality associated with this disorder is minor.

RISK INCREASES WITH--None known; sufferers are otherwise healthy.

HOW TO PREVENT--No specific preventive measures.

What To Expect

DIAGNOSTIC MEASURES--

• Your own observation of symptoms (sometimes). The minor jaundice may be unnoticeable.
• Medical history and physical exam by a doctor.
• Laboratory blood studies of bilirubin and liver function.

APPROPRIATE HEALTH CARE--None necessary.

POSSIBLE COMPLICATIONS--No known complications.

PROBABLE OUTCOME--The condition is harmless.

How To Treat

GENERAL MEASURES----If you or others notice a yellowing of your eyes or skin--it may seem like a good suntan--see your doctor for a diagnosis. Some more serious conditions also begin with mild jaundice.

MEDICATION--Medicine is not necessary for this disorder.

ACTIVITY--No restrictions.

DIET--No special diet.

Call Your Doctor If

You or anyone else thinks your skin looks a bit yellow.